MEDICINAL CHEMISTRY 715

30:715:307 Pharmaceutical Chemistry (2)
Introduces structure, properties, and analysis of pharmaceutical agents and metabolites as well as the fundamental techniques used for near patient testing in clinical laboratories.

30:715:360 Pharmaceutical Biochemistry (2)
Introduction to drug interaction in basic biochemical processes. Includes enzyme inhibitors, antimetabolites, and detoxification enzymes.
Prerequisite: 11:115:301.

30:715:409-410 Medicinal Chemistry I, II (3,3)
Study of organic medicinal and pharmaceutical compounds, with special emphasis on the correlation of structural and physiochemical properties with biological activity.
30:718:320

30:715:450 Drugs: Structure and Function (3)
Provides a survey of the major pharmaceutical agents in clinical use. Emphasis is placed on the influence of chemical structure in the elicitation of pharmacological effects.
Prerequisite: Undergraduate organic chemistry.

30:715:451 Foundations In Drug Discovery (3)
Basic course for students preparing to do research in medicinal chemistry. Topics covered include information management, computer methods, basic laboratory techniques, bioassay techniques, metabolism, prodrugs, and quantitative structure-activity relationships.
Prerequisite: Undergraduate organic chemistry.

30:715:452 Principles of Drug Design (3)
Topics covered include identifying new drug leads, drug absorption and distribution, pharmacomodulation, enzymes and receptors as targets, peptidomimetics, computer-aided drug design, and combinatorial chemistry.
Prerequisite: Undergraduate organic chemistry.

30:715:453 Herbal Medicines and Nutraceuticals (2)
Introduction to basic aspects of natural products chemistry as well as mechanisms associated with absorption, distribution, metabolism, and excretion of endogenous compounds and xenobiotics. Topics covered include disease states wherein herbal medicines and nutraceuticals have been suggested as having beneficial effects.

30:715:454 Heterocycles in Medicinal Chemistry
This course provides a discussion of the properties, reactions, and synthesis of the major classes of heterocyclic compounds, including sugars, which comprise most drugs in
clinical use.
01:160:307-308

30:715:495,496,497,498 Research in Medicinal Chemistry (BA)
Undergraduate research in medicinal chemistry.
Prerequisite: Permission of instructor. No more than two semesters of research courses may be used to satisfy degree requirements.